<mxfile host="app.diagrams.net"><diagram name="roadmap"><mxGraphModel dx="1422" dy="794" grid="1" gridSize="10" guides="1" tooltips="1" connect="1" arrows="1" fold="1" page="1" pageScale="1" pageWidth="1169" pageHeight="826" math="0" shadow="0">
  <root>
    <mxCell id="0" />
    <mxCell id="1" parent="0" />
    
    
    <mxCell id="node1" value="开发比色法DMS传感器" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#DAE8FC;strokeColor=#6C8EBF;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="201" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node1_desc" value="无需显色试剂与仪器，肉眼可读" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="40" y="40" width="222" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node2" value="核心策略" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D5E8D4;strokeColor=#82B366;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="481" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node2_desc" value="敲除crtA，置其于ddhA启动子下" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="332" y="40" width="222" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node3" value="关键改造" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#FFE6CC;strokeColor=#D79B00;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="761" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node3_desc" value="宿主固有色素胞内转化产生信号" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="624" y="40" width="222" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node4" value="关键结果" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D4E6F1;strokeColor=#2980B9;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1041" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node4_desc" value="检测限3 μM，颜色黄→红" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="916" y="40" width="210" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node5" value="结论与应用" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#E8D5F5;strokeColor=#9966CC;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1321" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node5_desc" value="适配海洋养殖环境，扩展至其他水质指标" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1196" y="40" width="278" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node6" value="传感机制验证" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#FFF2CC;strokeColor=#D6B656;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1601" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node6_desc" value="ddhA mRNA受DMS诱导，类胡萝卜素比例变化" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1544" y="40" width="292" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node7" value="定量色彩分析" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F8CECE;strokeColor=#B85450;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1881" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node7_desc" value="CIE LAB色度a* 1.53→2.30，色相80.7°→75.2°" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="1906" y="40" width="334" height="64" as="geometry" />
    </mxCell>
    
    
    <mxCell id="node8" value="检测条件优化" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D5F5E3;strokeColor=#27AE60;fontSize=14;fontStyle=1;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="2161" y="214" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node8_desc" value="指数期细胞，OD≥4.3，孵育1天" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F5F5F5;strokeColor=#999999;fontSize=11;verticalAlign=middle;" vertex="1" parent="1">
      <mxGeometry x="2310" y="40" width="222" height="64" as="geometry" />
    </mxCell>
    
    
    
    <mxCell id="edge1" edge="1" parent="1" source="node1" target="node2" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    
    <mxCell id="edge2" edge="1" parent="1" source="node2" target="node3" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    
    <mxCell id="edge3" edge="1" parent="1" source="node3" target="node4" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    
    <mxCell id="edge4" edge="1" parent="1" source="node4" target="node5" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry">
        </mxGeometry>
    </mxCell>
    
    
    <mxCell id="edge5" edge="1" parent="1" source="node4" target="node6" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=1;entryDx=0;entryDy=0;strokeColor=#888888;dashed=1;">
      <mxGeometry relative="1" as="geometry">
        </mxGeometry>
    </mxCell>
    
    
    <mxCell id="edge6" edge="1" parent="1" source="node6" target="node7" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    
    <mxCell id="edge7" edge="1" parent="1" source="node7" target="node8" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=1;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;strokeColor=#666666;">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    
    <mxCell id="edge8" edge="1" parent="1" source="node8" target="node1" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=1;entryDx=0;entryDy=0;strokeColor=#999999;dashed=1;">
      <mxGeometry relative="1" as="geometry">
        </mxGeometry>
    </mxCell>
  </root>
</mxGraphModel></diagram></mxfile>