<mxfile host="app.diagrams.net"><diagram name="roadmap"><mxGraphModel dx="1422" dy="794" grid="1" gridSize="10" guides="1" tooltips="1" connect="1" arrows="1" fold="1" page="1" pageScale="1" pageWidth="1600" pageHeight="900" math="0" shadow="0">
  <root>
    <mxCell id="0" />
    <mxCell id="1" parent="0" />
    <mxCell id="node1" value="问题：主要人参皂苷生物转化为稀有皂苷效率低" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D6E8F7;strokeColor=#1E6FA8;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="50" y="40" width="320" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node2" value="策略：克隆BglAm并异源表达" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D5E8D4;strokeColor=#2F7A3E;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="105" y="162" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node3" value="关键改造：GST亲和纯化体系" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#D5E8D4;strokeColor=#2F7A3E;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="105" y="284" width="210" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node4" value="酶学表征：最适pH 7.0，温度37°C，Km、Vmax测定" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#FFF2CC;strokeColor=#B08B2E;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="40" y="406" width="340" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node5" value="结果：8种转化途径，Rb1→Rh2首次实现" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#F8D7DA;strokeColor=#B02A37;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="74" y="528" width="271" height="64" as="geometry" />
    </mxCell>
    <mxCell id="node6" value="结论：GH3家族多功能酶，可生产多种稀有皂苷" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#E2D9F3;strokeColor=#5C3E8F;fontSize=14;fontStyle=1;verticalAlign=middle;align=center;spacing=6;" vertex="1" parent="1">
      <mxGeometry x="54" y="650" width="313" height="64" as="geometry" />
    </mxCell>
    <mxCell id="edge1" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeColor=#1E6FA8;" edge="1" parent="1" source="node1" target="node2">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    <mxCell id="edge2" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeColor=#2F7A3E;" edge="1" parent="1" source="node2" target="node3">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    <mxCell id="edge3" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeColor=#2F7A3E;" edge="1" parent="1" source="node3" target="node4">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    <mxCell id="edge4" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeColor=#B02A37;" edge="1" parent="1" source="node4" target="node5">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    <mxCell id="edge5" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;strokeColor=#5C3E8F;" edge="1" parent="1" source="node5" target="node6">
      <mxGeometry relative="1" as="geometry">
        </mxGeometry>
    </mxCell>
  </root>
</mxGraphModel></diagram></mxfile>