<mxfile host="app.diagrams.net"><diagram name="roadmap"><mxGraphModel dx="1422" dy="794" grid="1" gridSize="10" guides="1" tooltips="1" connect="1" arrows="1" fold="1" page="1" pageScale="1" pageWidth="1400" pageHeight="800" math="0" shadow="0">
  <root>
    <mxCell id="0" />
    <mxCell id="1" parent="0" />
    
    <mxCell id="n1" value="核心问题：补料策略与底物浓度如何影响CTX产量" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#dae8fc;strokeColor=#6c8ebf;fontSize=13;fontStyle=1;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="398" y="40" width="327" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n2" value="研究策略：比较CFR与EFR补料策略" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="284" y="162" width="236" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n3" value="实验设计：5L反应器，EHM浓度30、45、60 g/L" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="200" y="284" width="313" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n4" value="关键改造：酶解糖蜜完全替代葡萄糖作为碳源" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#f8cecc;strokeColor=#b85450;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="40" y="406" width="306" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n5" value="结果1：CFR（7 ml/h，45 g/L）最优" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#e1d5e7;strokeColor=#9673a6;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="590" y="162" width="250" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n6" value="结果2：BDW 17.66 g/L，TC 16.31 mg/L，CTX 14.67 mg/L" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#e1d5e7;strokeColor=#9673a6;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="584" y="284" width="340" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n7" value="结果3：比文献提高12.1%~22.8%，EFR效果差" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#e1d5e7;strokeColor=#9673a6;fontSize=12;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="416" y="406" width="299" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n8" value="结论：CFR策略+45 g/L EHM实现最高CTX产量" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#fff2cc;strokeColor=#d6b656;fontSize=13;fontStyle=1;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="785" y="406" width="299" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="n9" value="应用前景：EHM为葡萄糖廉价替代品，具工业潜力" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#fff2cc;strokeColor=#d6b656;fontSize=13;fontStyle=1;verticalAlign=middle;align=center;arcSize=10;" vertex="1" parent="1">
      <mxGeometry x="398" y="528" width="327" height="64" as="geometry" />
    </mxCell>
    
    <mxCell id="e1" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n1" target="n2">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e2" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n2" target="n3">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e3" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n3" target="n4">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e4" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n1" target="n5">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e5" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0;exitY=0.5;exitDx=0;exitDy=0;entryX=0;entryY=0.5;entryDx=0;entryDy=0;dashed=1;dashed=1;" edge="1" parent="1" source="n4" target="n6">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e6" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n5" target="n6">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e7" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n6" target="n7">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e8" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n6" target="n8">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
    <mxCell id="e9" style="edgeStyle=orthogonalEdgeStyle;rounded=1;orthogonalLoop=1;jettySize=auto;html=1;endArrow=block;endFill=1;strokeWidth=1.6;exitX=0.5;exitY=1;exitDx=0;exitDy=0;entryX=0.5;entryY=0;entryDx=0;entryDy=0;" edge="1" parent="1" source="n8" target="n9">
      <mxGeometry relative="1" as="geometry" />
    </mxCell>
    
  </root>
</mxGraphModel></diagram></mxfile>