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    <mxCell id="node2" value="策略：秋水仙碱处理未成熟胚诱导多倍体，建立四倍体细胞系；流式细胞术确认倍性，比较不同倍性细胞系" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#d5e8d4;strokeColor=#82b366;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node3" value="关键改造1：0.05%秋水仙碱最适，获得四倍体细胞系，伸长的细胞3.33倍、圆形细胞2.99倍" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node4" value="关键改造2：多倍化上调紫杉烷合成基因（GGPPS 1.76倍、TXS 2.84倍、DBAT 9.1倍、BAPT 7.17倍、DBTNBT 53.2倍）" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#ffe6cc;strokeColor=#d79b00;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node5" value="结果1：四倍体细胞系第8天总紫杉烷产量21.64 mg/L（二倍体6.2倍），峰值提前8天，胞外10.8倍" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#fff2cc;strokeColor=#bf9000;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node6" value="结果2：多倍体化增强紫杉烷外排：胞内含量低2.5倍，胞外高10.8倍" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#fff2cc;strokeColor=#bf9000;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node7" value="结果3：秋水仙碱浓度影响：0.1%致死72%、0.05%致死68%、0.01%发芽63%（对照70%）" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#fff2cc;strokeColor=#bf9000;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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    <mxCell id="node8" value="结论：四倍体细胞系大幅提高紫杉烷产量与外排，基因表达全面上调，为可持续生产紫杉醇提供新策略" style="rounded=1;whiteSpace=wrap;html=1;fillColor=#f8cecc;strokeColor=#b85450;fontSize=12;fontStyle=1;verticalAlign=middle;align=center;spacing=5;" vertex="1" parent="1">
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